用于智能流体控制的水凝胶致动式微型阀

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用于智能流体控制的水凝胶致动式微型阀AbstractóIn this paper， we report on the fabrication and
testing of a hydrogel-actuated smart microvalve for biomedical
applications. The three-layered microvalve is composed of a
stimuli-sensitive ìintelligentîhydrogel sandwiched between a
porous silicon membrane and a bossed PDMS flexible
diaphragm. The entrapped hydrogel in response to changes in
the external physiological stimuli (e.g.， pH， glucose， etc.)， which
diffuses through the porous membrane， swelles and deswelles
hence deflecting the flexible PDMS diaphragm and controlling
the closure and opening of the microvalve inlet. A microvalve
incorporating a 155µm thick hydrogel (poly(methacrylic
acid-co-acrylamide)， mAA-co-AAm) has a response time of
3.6min to a sudden pH change (pH3 to pH7).
KeywordsóHydrogel， pH-sensitive， microvalve， flow
control， microfluidics， PDMS.